Kienan I. Savage: search on Z-Library

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1

BRCA1, a ‘complex’ protein involved in the maintenance of genomic stability

Savage, Kienan I., Harkin, D. Paul

Journal:

Year:

2015

Language:

english

File:

PDF, 573 KB

english, 2015

2

The effect of clinical and tumour factors on prognosis after contralateral breast cancer (CBC) in Northern Ireland (NI)

McIlmunn, Colin, Bannon, Finian, Fitzpatrick, Deirdre, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2018

Language:

english

File:

PDF, 52 KB

english, 2018

3

27. Multifocality in BRCA-associated breast cancer: a cross-sectional analysis

McCrorie, Alan, Ashfield, Susannah, McIlmunn, Colin, Boyd, Clinton, Savage, Kienan, Morrison, Patrick, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2019

Language:

english

File:

PDF, 83 KB

english, 2019

4

Bilateral synchronous breast cancer: Histological concordance and surgical management

Dobson, Gary, McIlmunn, Colin, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2017

Language:

english

File:

PDF, 33 KB

english, 2017

5

27. Multifocality in BRCA-associated breast cancer: a cross-sectional analysis

McCrorie, Alan, Ashfield, Susannah, McIlmunn, Colin, Boyd, Clinton, Savage, Kienan, Morrison, Patrick, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2019

File:

PDF, 83 KB

2019

6

Incidence and clinical characteristics of contralateral breast cancer (CBC) in Northern Ireland: A population-based study

McIlmunn, Colin, Fitzpatrick, Deirdre, Murray, Liam, Harkin, Paul, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2017

Language:

english

File:

PDF, 39 KB

english, 2017

7

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Savage, Kienan I., Gorski, Julia J., Barros, Eliana M., Irwin, Gareth W., Manti, Lorenzo, Powell, Alexander J., Pellagatti, Andrea, Lukashchuk, Natalia, McCance, Dennis J., McCluggage, W. Glenn, Schet

Journal:

Year:

2014

Language:

english

File:

PDF, 4.22 MB

english, 2014

8

Chemoprevention in BRCA1 mutation carriers (CIBRAC): protocol for an open allocation crossover feasibility trial assessing mechanisms of chemoprevention with goserelin and anastrozole versus tamoxifen and acceptability of treatment

Campbell, Aideen M, Morris, Melanie, Gallagher, Rebecca, Boyd, Ruth, Carson, Hazel, Harkin, D Paul, Wielogorska, Ewa, Elliott, Christopher, Savage, Kienan I, McIntosh, Stuart A

Journal:

Year:

2018

Language:

english

File:

PDF, 748 KB

english, 2018

9

P143. SF3B1 mutation is a predictor of BRCAness in ER positive breast cancer

Irwin, Gareth, Savage, Kienan, Harkin, Paul

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2015

Language:

english

File:

PDF, 54 KB

english, 2015

10

Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis

Nyree Crawford, Alex D. Chacko, Kienan I. Savage, Francis McCoy, Kelly Redmond, Daniel B. Longley, Dean A. Fennell

Journal:

Year:

2011

Language:

english

File:

PDF, 584 KB

english, 2011

11

P051. Clinico-pathological features of Synchronous Breast Cancers in Northern Ireland, 2000-2015

Dobson, Gary, McIlmunn, Colin, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2019

File:

PDF, 48 KB

2019

12

Incidence and clinical characteristics of contralateral breast cancer (CBC) in Northern Ireland: A population-based study

McIlmunn, Colin, Fitzpatrick, Deirdre, Murray, Liam, Harkin, Paul, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2018

Language:

english

File:

PDF, 41 KB

english, 2018

13

Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control

Vohhodina, Jekaterina, Harkin, D. Paul, Savage, Kienan I.

Journal:

Wiley Interdisciplinary Reviews: RNA

Year:

2016

Language:

english

File:

PDF, 871 KB

english, 2016

14

Contralateral breast cancer in Northern Ireland: A retrospective review from 1993 to 2016

McIlmunn, Colin, Fitzpatrick, Deirdre, Savage, Kienan, Murray, Liam, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2017

Language:

english

File:

PDF, 41 KB

english, 2017

15

PARP inhibition induces BAX/BAK-independent synthetic lethality of BRCA1-deficient non-small cell lung cancer

Ian Paul, Kienan I Savage, Jaine K Blayney, Elisabeth Lamers, Kathy Gately, Keith Kerr, Michael Sheaff, Kenneth Arthur, Derek J Richard, Peter W Hamilton, Jacqueline A James, Kenneth J O'Byrne, D Paul

Journal:

The Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 421 KB

english, 2011

16

P051. Clinico-pathological features of Synchronous Breast Cancers in Northern Ireland, 2000-2015

Dobson, Gary, McIlmunn, Colin, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2019

Language:

english

File:

PDF, 48 KB

english, 2019

17

Chronic loss of STAG2 leads to altered chromatin structure contributing to de-regulated transcription in AML

Smith, James S., Lappin, Katrina M., Craig, Stephanie G., Liberante, Fabio G., Crean, Clare M., McDade, Simon S., Thompson, Alexander, Mills, Ken I., Savage, Kienan I.

Journal:

Journal of Translational Medicine

Year:

2020

File:

PDF, 9.94 MB

2020

18

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export

Vohhodina, Jekaterina, Barros, Eliana M., Savage, Abigail L., Liberante, Fabio G., Manti, Lorenzo, Bankhead, Peter, Cosgrove, Nicola, Madden, Angelina F., Harkin, D. Paul, Savage, Kienan I.

Journal:

Nucleic Acids Research

Year:

2017

Language:

english

File:

PDF, 7.44 MB

english, 2017

19

Impact of Variable RNA-Sequencing Depth on Gene Expression Signatures and Target Compound Robustness: Case Study Examining Brain Tumor (Glioma) Disease Progression

Stupnikov, Alexey, O’Reilly, Paul G., McInerney, Caitriona E., Roddy, Aideen C., Dunne, Philip D., Gilmore, Alan, Ellis, Hayley P., Flannery, Tom, Healy, Estelle, McIntosh, Stuart A., Savage, Kienan,

Journal:

JCO Precision Oncology

Year:

2018

Language:

english

File:

PDF, 1.47 MB

english, 2018

20

Protein kinase C zeta suppresses low- or high-grade colorectal cancer (CRC) phenotypes by interphase centrosome anchoring

Deevi, Ravi Kiran, Javadi, Arman, McClements, Jane, Vohhodina, Jekaterina, Savage, Kienan, Loughrey, Maurice Bernard, Evergren, Emma, Campbell, Frederick Charles

Journal:

The Journal of Pathology

Year:

2018

Language:

english

File:

PDF, 2.49 MB

english, 2018

21

Understanding the genetic relationship between primary and contralateral breast cancer (CBC) could present opportunities for personalised surgery

McIlmunn, Colin, Gonzalez de Castro, David, James, Jacqueline, Fitzpatrick, Deirdre, Savage, Kienan, McIntosh, Stuart

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2018

Language:

english

File:

PDF, 73 KB

english, 2018

22

Homologous Recombination Deficiency in Breast Cancer: implications for risk, cancer development and therapy

Ali, Rayhaan M.M., McIntosh, Stuart A., Savage, Kienan I.

Journal:

Genes, Chromosomes and Cancer

Year:

2020

File:

PDF, 2.04 MB

2020

23

Single-stranded DNA-binding protein hSSB1 is critical for genomic stability

Richard, Derek J., Bolderson, Emma, Cubeddu, Liza, Wadsworth, Ross I. M., Savage, Kienan, Sharma, Girdhar G., Nicolette, Matthew L., Tsvetanov, Sergie, McIlwraith, Michael J., Pandita, Raj K.

Journal:

Year:

2008

Language:

english

File:

PDF, 873 KB

english, 2008

24

Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer

Parkes, Eileen E., Walker, Steven M., Taggart, Laura E., McCabe, Nuala, Knight, Laura A., Wilkinson, Richard, McCloskey, Karen D., Buckley, Niamh E., Savage, Kienan I., Salto-Tellez, Manuel, McQuaid,

Journal:

JNCI Journal of the National Cancer Institute

Year:

2017

Language:

english

File:

PDF, 1.74 MB

english, 2017

25

BRCA ‘variants of unknown significance’ need regular review to facilitate optimal patient management

Irwin, Gareth, Freitas, Cassandra, McIntosh, Stuart, Savage, Kienan

Journal:

European Journal of Surgical Oncology (EJSO)

Year:

2017

Language:

english

File:

PDF, 40 KB

english, 2017

26

The Nuclear Oncogene SET Controls DNA Repair by KAP1 and HP1 Retention to Chromatin

Kalousi, Alkmini, Hoffbeck, Anne-Sophie, Selemenakis, Platonas N., Pinder, Jordan, Savage, Kienan I., Khanna, Kum Kum, Brino, Laurent, Dellaire, Graham, Gorgoulis, Vassilis G., Soutoglou, Evi

Journal:

Year:

2015

Language:

english

File:

PDF, 5.33 MB

english, 2015

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